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An exclusive interview with Alex Michine, CEO of MetGen. “Building consumer awareness is key for the expansion of the European bioeconomy”

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MetGen is a Finnish company headquartered in Kaarina and founded in 2008 on the core competence of genetic engineering and synthetic biology.

In this exclusive interview with Il Bioeconomista, the CEO, Alex Michine, talks about the achievements and the next steps of the company and gives us his point of view regarding the bioeconomy in Finland and in the European Union.
Interview by Mario Bonaccorso

MetGen claims that “everything that is made from oil today, can be made of wood tomorrow”. How can this be possible?

MetGen’s goal is to refine lignin and produce ‘drop-in’ replacements for fossil-based chemicals – rather than produce the same fossil-based chemicals. For example, we want to replace formaldehyde in polyurethane foams with lignin fractions. Processing wood fractions – especially lignin – is similar to prerefining oil. However, MetGen can replace complicated operations with simpler, more streamlined processes by converting side streams of lignocellulosic biomass into valuable renewable chemicals and building blocks. Our vision is to enable various industries to get the most value out of biomass, thereby helping them decarbonise.

The market of enzymes is dominated by the Danish biotech giant Novozymes. But it is a market which is attracting many chemical companies, such as BASF and Dupont. What is your strategy to grow in this market?

No single company can fully address the needs of modern biorefineries and we all need to work together to enable a variety of solutions. We are fans of open innovation and working together with other companies and Research Technology Organisations (RTOs).

At MetGen, we’re focused on customising all our enzymatic solutions to our customer process and providing a cocktail of solutions. Processed biomass is like the soup of the day – never the same. Different biomass is pre-treated with different methods and it all undergoes different processes, so we know it doesn’t make sense to create an ‘off-the-shelf’enzymatic solutions.

How does your two technologies Metnin and Enzine work?

ENZINE® is a platform combining protein evolution technology and fermentation, which significantly reduces the technology development cycle of enzymes focused on biomass. It is enzyme agnostic, meaning it can be used to create and improve any enzyme, therefore allowing for tailored solutions.

METNIN enables products made from lignin to have a reduced carbon footprint. The enzyme technology facilitates lignin valorisation in industrial and commercial applications and it is unique due to MetGen’s proprietary enzyme strain working in extreme conditions, including high temperature and pH. A versatile technology, it extends lignin’s application scope.

Frost & Sullivan recognized your company with the 2019 European Technology Innovation Award for your two enzyme technologies. What does this award mean for your company and what are your next steps to develop your business?

We were delighted that Frost & Sullivan recognised our technologies as best-in-class – it means our strategy and vision is working to enable bio-based solutions. The award also recognised the MetGen team’s hard work, which a huge boost to our team spirit.

Recognition from such a prestigious organisation naturally helps raise awareness of our technologies and helps us develop a wider customer base. The award also helps build awareness of more sustainable technologies, which will ultimately help society reduce its dependence on fossil fuels.

MetGen is a Finnish company and Finland is probably one of the best places in Europe for the bioeconomy. How much is important for your business the Finnish political and economic environment?

Finland is a great place to set up a start-up, as the country has deep bio-based knowhow, especially on processing biomass in an environmentally-friendly way. What can be improved in Finland – as well as the rest of the EU – is the availability of financing for pilot and demonstration facilities. Luckily, BBI JU, the public-private partnership between the EU and the Bio-based Industries Consortium (BIC), is a mechanism which provides this support. We hope the next Horizon Europe programme will be even bigger, as this the only way to accelerate bio-based products’ commercialisation in Europe.

And what do you think is still needed in Europe to grow the bioeconomy?

Building consumer awareness is key for the expansion of the European bioeconomy. European society needs to gain a common understanding on the importance of bio-based solutions and their impact on sustainability and circularity.

We do not believe green solutions should cost a premium price – bio-based solutions need to be widely available and competitively-priced. Brand owners should adapt their strategies to boost market pull for renewable chemicals and products. Once this happens, additional investments by private equity and banks could be injected to accelerate bioeconomy adoption.

MetGen Earns Acclaim from Frost & Sullivan for its Unique, Customized Enzyme Technologies, METNIN™ and ENZINE®

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The technologies solve the industry’s major pain points regarding the valorization of lignin, shorter technology development cycles, and customization of enzymes for different applications

Based on its recent analysis of the European industrial enzymes market, Frost & Sullivan recognizes Finland-based MetGen with the 2019 European Technology Innovation Award for its enzyme technologies, METNIN™ and ENZINE®. METNIN™ enables complete valorization of lignin for use in various applications, allowing the products made of lignin to be more sustainable and have a reduced carbon footprint. Unlike most competing solutions, it can also depolymerize and activate lignin under harsh conditions, such as alkaline pH (pH~11). Uniquely, it helps users tailor other properties such as solubility to water or solvents, polarity, and glass transition temperature.

ENZINE®,  meanwhile, can be used to improve any enzyme, but MetGen made a strategic decision to target it at enzymes for biomass processing. This platform significantly reduces the technology development cycle of enzymes focused on biomass. Furthermore, the company’s process and business model presents flexible production options, including on-site manufacturing. Its other enzyme technologies include MetZyme®BRILA™ and MetZyme®POVON™, which can be tailored to fit applications in different industries, such as pulp & paper.

“MetGen leverages its strong R&D capabilities as well as its manufacturing facilities in Europe to meet all customer demands,” said Aarthi Janakiraman Industry Manager, TechVision. “It has signed a licensing and joint technology development agreement with several industrial partners and other technology providers to develop a full range of lignin-based products including resins, composites, bio-based chemicals, and polymers.”

The enzymes are developed to perform under challenging conditions such as high temperatures and extreme pH values, which are common in industrial biorefineries. Therefore, the enzymes can be used with process parameters beyond typical enzyme-related restrictions. Besides, the solutions enhance the feasibility of lignocellulosic chemical production, including biofuels. They also augment the sugar yields, eliminate inhibitors, and raise the overall process economy. For the water and biogas industry, MetGen has developed different enzymatic solutions that can accelerate processes by breaking down triglycerides and cellulosic materials into fatty acids and neutralizing toxic compounds like peroxides.

“MetGen is one of few companies in the industrial enzymes segment that can customize enzyme solutions for different sectors, such as pulp & paper and biorefineries. The superior features of its enzymes and its wide application landscape are its key value propositions and have increased its brand awareness among its target industry customers,” noted Janakiraman. “Ultimately, the company’s robust R&D and unmatched technology have given it the momentum needed to firmly establish itself and maintain its dominance of the industrial enzymes market.”

Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables.

About MetGen

MetGen Oy is an innovative biotech SME who designs, develops, supplies and markets novel enzymatic solutions and technologies around them for the most challenging of industrial conditions to meet our customer-specific needs. MetGen was found in 2008 and is based in Kaarina, Finland. The company is currently backed by some of the leading venture capital investors and industrial partners. MetGen is a member of the Bio-based Industries Consortium and a consortium member to 11 EU Horizon2020 projects ranging from R&D efforts to Flagship factories.

MetGen uses advances in genetic engineering and microbiology to adapt enzymes to harsh industrial conditions and to handle a variety of lignocellulosic substrates to fulfill the company’s mission: Empower industries to maximize the value out of biomass.

MetGen’s enzyme products – MetZymes® – are industrial, highly-active, natural catalysts that accelerate chemical reactions. They can survive in harsh industrial environments which enables novel applications and disruptive new technologies, such as METNIN™ for lignin valorization. The products and technologies are protected by international patents.

MetGen has created a disruptive technology platform, ENZINE®, to develop industrial enzymes at a world-leading speed and unparalleled efficiency. The company has achieved industrial successes with sector leaders in forest and renewable chemicals. The team aspires to be a widely recognized and preferred supplier of industrial enzymes, significantly contributing to the economics and sustainability of process industries such as pulp & paper, biofuels, and biochemicals.

MetGen is readily prepared to address the full value-chain in bioprocessing – from feedstock to consumer goods and valorization of side streams – with its MetZyme® product portfolio.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today’s market participants. For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector, and the investment community. Contact us: Start the discussion.


Lindsey Whitaker
P: +1 (210) 477-8457

MetGen’s hydrolysis and novel lignin valorisation technologies utilised in UNRAVEL biorefinery demonstrator– Driving on bark, building with nutshells

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Over the next four years the European UNRAVEL project will demonstrate a sustainable and economically feasible biorefinery for the conversion of second generation biomass into fuels, chemicals and building materials. In their efforts the partnership that comprises research organisations, SMEs and large industry from six European countries are supported by the Bio Based Industries Joint Undertaking (BBI JU) which funds the UNRAVEL project with 3.6 million Euros.

The Bio-based Industries Consortium (BIC) and the European Union’s ‘Horizon 2020’ Research and Innovation Framework Programme, both co-funding bodies of the BBI JU, have developed strategic agendas to realise the European transition towards a post-petroleum society while decoupling economic growth from resource depletion and negative environmental impacts. A key task is the creation of novel bio-based value chains by developing new biorefinery technologies and optimising the use of sustainable feedstock for innovative added-value products that respond to market needs. The project will also contribute to the development of new building blocks for different bio-based products from biomass of European origin.

One of the major challenges in creating long-term benefits is to find sustainable and industrially viable biomass that does not compete with land-use for food production or that could pose the risk of natural habitat loss. One promising solution lies in using biomass residues that originate from forestry and/or agriculture such as bark, wheat straw or nutshells. The potential availability of these residues is substantial with estimates of around 180 Mton per year within the EU. Agricultural residues and wheat straw represent approximately half of the total available amount. Components within these residues that are of major economic interest are sugars and lignin, a substance with which bio-based materials and biochemicals can be developed. The UNRAVEL project will target sugar as compound for advanced liquid biofuels for transport and lignin for building blocks for bio-based materials, such as bio-polymers, insulation foams (polyurethane) and bitumen.

Project key facts:

UNRAVEL  started on the 1st June 2018 and will run for four years. The project is coordinated by Fraunhofer Gesellschaft and ECN (part of TNO). The consortium comprises ten partners from seven European countries.

For further details

UNRAVEL Project Coordination Contacts:

Moritz Leschinsky      
Fraunhofer CBP
Am Haupttor
06237 Leuna
Tel: +49 (0)3461 43 9102

Jaap van Hal
ECN part of TNO
P.O. Box 1
1755 ZG Petten
The Netherlands
Tel: +31-(0)88-866 2652

UNRAVEL can also be found on Twitter, LinkedIn and Facebook:   


This project has received funding from the European Union’s Horizon 2020/BBI-JU research and innovation programme under grant agreement No 792004


METGEN Lignin valorisation technologies applied in Bio-Based Industries project WoodZymes

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Industrial enzyme solution provider MetGen Lignin valorisation technologies are utilised in European Project WoodZymes, “Extremozymes for wood-based building blocks: from pulp mill to board and insulation products”. This is a H2020 Research & Innovation Action funded with € 3.25 million by the “Bio-Based Industries” Joint Undertaking (

The project goal is to develop tailor-made enzymes able to work under the extreme operation conditions of pH and temperature required by the wood-processing industries to remove or modify hemicelluloses and recalcitrant lignin protecting cellulose in the plant cell wall. This will enable selective valorisation of currently underutilised biomass fractions to provide high-value bio-equivalents of petroleum-derived chemical building blocks.

Enzyme application will include the recovery of phenolic compounds from enzymatic breakdown of technical lignin, and the extraction of lignin and hemicellulose compounds from enzymatic delignification and bleaching of kraft pulp. Extremophilic enzymes will also be used to valorise these compounds as bio-based precursors for adhesives in the manufacture of medium-density fibreboards, and as components of insulation polyurethane foams, as well as for obtaining renewable sugar-based papermaking additives. As shown in the figure below, WoodZymes illustrates the potential of extremozymes in the global bio-based economy, contributing to the sustainability and competitiveness of cellulose, fibreboard and polyurethane manufacture, and establishing a direct link between pulp and wood industrial sectors.

Consortium of the wood, cellulose, lignin and enzyme sectors from Portugal, France, Finland and Spain, is formed. Within this ambitious project with MetGen, a strong European cooperation is applied with world-leading companies of the sectors of pulp & paper (The Navigator Company and Fibre Excellence), fibreboard manufacture (FINSA France) and insulation materials (Soprema), several research institutes (CIB, IRNAS and IATA from CSIC), and technology centres (RAIZ, CTP and FCBA).


More information:

Follow us in Twitter: @WoodZymes

Contributing to the Bio-based Economy: The WoodZymes project covers the entire value chain from forest biomass (hardwood and softwood) to phenolic and sugar-derived equivalents of fossil-derived chemicals for the manufacture of medium-density fibreboard, polyurethane insulation foam and bleached paper, through the transformation of underutilised lignin and hemicellulose fractions extracted from pulp mills with tailor-made extremophilic enzymes.

This project has received funding from the Bio Based Industries Joint Undertaking (JU) under grant agreement No 792070. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the Bio Based Industries Consortium.

MetGen Industrializes 4 Novel Enzymatic Technologies at Once in Integrated Biorefinery Flagship Project

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Kaarina, Finland, MetGen – industrial enzyme solution provider, is moving forward in an industrial demonstration of it’s four novel biorefinery solutions: Tailored hydrolysis solution, Enzymatic lignin depolymerization, Lignocellulosic glucose isomerization, and Glucose conversion to glucosone. The demonstration takes place as a part of partially publicly funded EU Flagship project SWEETWOODS.

SWEETWOODS is a 43-million-euro joint pilot project that was recently granted 21 million euros in funding under the EU’s Horizon 2020 programme’s Bio-Based Industries financial instrument. Horizon 2020 is the biggest research and innovation programme in the world, supporting the development and introduction of new technologies. Industry consortium led by OÜ Graanul Biotech and bringing together MetGen Oy, Global Bioenergies, Tecnaro GmbH, Armacell via Ultima GmbH, Recticel N.V., 2B Srl, Vertech Group and Spinverse Oy. SWEETWODS aims at establishing a completely unique wood fractionation Flagship plant and demonstration of novel value-chains based on sustainable hardwood resource.

“Receiving the EU funding is a major victory for all parties involved in the project and a testament to our tireless efforts. Specialists representing the European Union and bioindustries ranked the project as the best of the round of financing, giving the project full marks,” describes Peep Pitk, the R&D Manager of the Estonian Graanul Invest Group.

MetGen has worked for years to create technology platforms and an ecosystem where a financially sound biorefinery concept could be materialized. MetGen‘s role in this has been two-fold: MetGen has consistently worked towards bringing the relevant technologies towards commercial readiness and in parallel played a key role in bringing together like-minded organizations under a shared vision. Teamwork in a vast network of operators has helped MetGen to identify the strongest teams and technologies to make up complete value-chains from raw materials to market. Furthermore, the close collaboration at every step along the way has allowed MetGen to identify the areas where enzymatic technologies can complement chemical and mechanical steps.

“The project allows us to produce with wood what is currently made with oil. In a matter of only a few years, consumers may have access to innovative products made out of wood-based plastics, foams, and composites.” comments MetGen’s Chief Technology Officer Matti Heikkilä.

MetGen brings to SWEETWOODS new biorefinery solutions that will be integrated into demonstration facility.

Tailored hydrolysis solution

Every biomass is unique. Therefore MetGen is ready and willing to make a tailored hydrolysis solution to address the pretreated biomass that not only provides high yields and purity for the sugar and lignin fractions but also enables value-addition to the further products.

Enzymatic Lignin Depolymerization and Modification

With first-of-a-kind Lignolytic enzymes, which not only tolerate but prefer highly alkalic conditions MetGen is able to enzymatically fractionate and activate lignin at pH 11 water-soluble conditions without organic solvents or heavy metal catalysts. Enabled by the mild conditions the valuable and specific low molecular weight fractions can be harvested using affordable and straightforward membrane technologies.

Lignocellulosic glucose isomerization

While Glucose Isomerase is one of the oldest industrial enzymes it has, until now, lacked the capabilities to function with lignocellulosic sugars. MetGen has developed a Glucose Isomerize which functions despite the inhibitors (xylose, mannose, galactose, lignin…) providing higher yields of fructose that the competing solutions achieve in purified food applications.

Glucose bioconversion to glucosone

Glucosone has been known as a rare sugar mostly used as an intermediate for antibiotics. However, when brought to affordable commodity prices it provides many useful routes to renewable chemicals: this intermediate sugar can be chemically converted to many interesting platform chemicals. Furthermore, glucose to glucosone conversion is a complete one-way reaction. If can be further hydrogenated to fructose allowing for streamlined processes without glucose-fructose separation and providing high-concentration fructose as an affordable and sustainable raw material for bioplastic applications. Glucosone is also microbiologically more inert than dilute glucose solutions, allowing many benefits in plant scale operations and engineering.

MetGen Appoints Martin Granholm as Chairman of its Board of Directors

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Kaarina, Finland, MetGen – industrial enzyme solution provider, has appointed Forest Industry expert Martin Granholm as Chairman of its board of Directors. MetGen serves pulp & paper and renewable chemicals markets by delivering sustainable enzymatic solutions, and Granholm brings deep expertise and experience to the company.

“Forest industry is undergoing major changes as global demand for traditional forest products shifts. While helping the forest sector adjust to changes in market needs, MetGen is also involved in building relative new industry sector – renewable chemicals. I am confident that Martin experience will have an immediate impact on the direction of the company’s strategic development. MetGen’s team is excited to have Martin on our board, and we look forward to his guidance and contributions” said Alex Michine, CEO of MetGen.”

Martin Granholm is a former Deputy CEO of UPM-Kymmene Oyj. During his 35 years in several positions in the Forest Industry, he also acted as member and chairman in the boards of various organizations in Logistics, Energy, University, and Insurance. Furthermore, he has held positions in the Chamber of Commerce organization both locally and globally.

“During my time in the Forest industry, I have seen wood as different types of fibers and chemicals. Today, when industries look for entering the bio-stage, MetGen’s enzymes provide a real key into this future – and not only in the Forest sector. The market is asking for renewable concepts, energy savings, product quality improvements and environmentally friendlier solutions. MetGen is perfectly positioned in this development. I look forward to participating in building on this opportunity together with the board and the whole MetGen organization “, said Granholm

Vuoden 2018 teknologiajohtajat valittiin: Planmecan Vesa Varjonen ja MetGenin Matti Heikkilä ovat vaikuttaneet suomalaisen teollisuuden uudistumiseen

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Embargo 16.3.2018 klo 9.00

Suomalaisista teknologiavaikuttajista koostuva tuomaristo on valinnut vuoden 2018 teknologiajohtajiksi Planmecan teknologia- ja tutkimusjohtajan Vesa Varjosen ja MetGenin teknologiajohtajan Matti Heikkilän.

Vuodesta 2010 lähtien myönnetty tunnustuspalkinto jaetaan 19.3. suuryritysten ja pk-yritysten kategorioissa. Tällä kertaa valinnassa painottuivat yritykset, jotka ovat omilla toimillaan uudistaneet suomalaista teollisuutta. ”Suomen teollisuus on voimakkaassa muutoksessa, ja pk-yrityksillä on tärkeä rooli uuden liiketoiminnan kasvattamisessa. Planmeca ja MetGen ovat tästä huippuesimerkkejä: Planmeca on tutkimukseen ja tuotekehitykseen panostamalla ja digitalisaatiota hyödyntämällä luonut koko alaa uudistavia innovaatioita. MetGen taas on lähtenyt rohkeasti kehittämään täysin uutta teknologiaa kansainvälisille markkinoille ja kyennyt rakentamaan vaikuttavan kumppaniverkoston taakseen, kuvaa tuomariston puheenjohtaja Laura Juvonen Teknologiateollisuus ry:stä.

Suomalaisen terveysteknologian vientiä maailmalle: Planmeca

Planmeca on yksi maailman johtavista hammashoitolaitteiden valmistajista, jonka tuotteita viedään yli 120 maahan. Vuonna 1971 perustettu terveysteknologiayritys on malliesimerkki yhtiöstä, joka kehittää dynaamisesti maailman johtavaa teknologiaa – yrityksessä kiteytyy suomalaisen valmistavan teollisuuden uudistuminen. ”Planmeca ei ole yrityksenä ikinä valmis, eivätkä tuotteemme koskaan lakkaa kehittymästä. Ilman tätä mentaliteettia innovointi organisaatiossa kuolee”, toteaa Planmecan perustaja ja toimitusjohtaja Heikki Kyöstilä. Terveysteknologia-ala kasvaa Suomessa ja liikevaihdosta suurin osa tulee viennistä.

Vesa Varjonen on työskennellyt jo yli 25 vuotta monenlaisissa tehtävissä lääketieteellisen kuvantamisen parissa. Planmecalla vuodesta 2004 työskennellyt Varjonen nousi teknologia- ja tutkimusjohtajaksi vuonna 2015. ”Kasvuhalu ja motivaatio huokuvat esimerkin voimasta. Vesa Varjonen on tällainen esimerkki. Hänessä yhdistyvät vahva osaaminen, teknologian ja tutkimusmaailman syvä ymmärrys sekä vuosikymmenten ammattitaito”, Kyöstilä kertoo. ”Nopeasti kehittyvässä maailmassa toimijoiden yhteistyön merkitys korostuu entisestään, ja tässä Vesan rooli on tärkeä. Vesa onkin aktiivisesti mukana tekemässä yhteistyötä eri yliopistojen, tutkimusryhmien ja startup-yritysten kanssa.”

Varjonen on koulutukseltaan lääketieteellisen tekniikan diplomi-insinööri. ”Palkintoraadin keskustelussa nousi myös esille, kuinka tärkeää monialainen koulutus ja osaaminen on tulevaisuuden teknologioiden kehittämisessä ja hyödyntämisessä”, toteaa Juvonen.

Malliesimerkki uudistavasta voimasta: MetGen

MetGen Oy on entsyymituottaja, jonka tuotteet palvelevat laajaa kirjoa toimijoita sellu- ja paperiteollisuudesta jätevedenpuhdistamiseen sekä biopolttoaineisiin. Cleantech-yrityksen valmistamien entsyymien valttikortti on geneettinen räätälöinti, joka auttaa niitä kestämään vaativiakin olosuhteita. MetGen on kyennyt kokoamaan merkittävän määrän julkista rahoitusta kehittääkseen kumppaniensa kanssa uusia kestäviä tapoja parempaan raaka-aineiden käyttöasteeseen ja prosessien parantamiseen.

”Teknologiajohtaja Matti Heikkilä on henkilönä erittäin hyvä verkottuja. Hän ei pelkää lähestyä isojakaan pelureita, mikä on tärkeä ominaisuus kasvukiidossa olevalle pk-yritykselle. Heikkilä on roolimalli muille pk-yrityksien teknologiajohtajille näyttäessään, kuinka uusia ekosysteemejä rakennetaan EU-tukea hyödyntäen ja miten Suomea uudistetaan luomalla uusia, kestäviä ratkaisuja teollisuuteen”, toteaa Juvonen.

MetGenin vahvuuksia on uusien ratkaisujen tuominen laboratorioista markkinoille. Useissa tapauksissa juuri Heikkilä on ollut ajamassa uusia tuotteita nopeasti käytännön sovelluksiin. ”Matti on käytännössä omin käsin luonut kokonaisen arvoketjun tyhjästä. Hän jatkaa edelleen periksiantamattomalla sykkeellä uusien teknologioiden luomista myynnin tukena”, kertoo MetGenin toimitusjohtaja Alex Michine. Heikkilän ansioiksi voidaan lukea MetGenin tuotekehitysalusta, jonka avulla MetGen kykenee tuomaan uusia tuotteita ideasta markkinoille alle viidessä kuukaudessa – maailman johtava tehokkuus alalla. Hänen johdollaan tuotteiden valmistusprosessin päästöt on saatu minimoitua käytännössä nollaan.

Heikkilä vastaa päätoimensa lisäksi MetGenillä markkinoinnista ja uusien liiketoimintojen kehityksestä. ”Matin rakentamat ekosysteemit maksimoivat kaikkien tahojen saaman hyödyn. Hänellä on uskomaton kyky muovata kokonaisia toimialoja visiollaan”, Michine hehkuttaa. ”On ällistyttävää, kuinka hän kykenee välittämään visiomme niin yrityksen sisällä kuin rahoittajienkin keskuudessa, erityisesti niinkin kompleksisella alalla kuin biotuoteteknologiassa.”


Palkintolautakunnan sihteeri Pekka Koponen, puh. 040 545 0008

Vesa Varjonen
Vice President, Research and Technology                                                                                        

Matti Heikkilä

Business Finland                                
Pekka Soini

Teknologiateollisuus ry
Laura Juvonen
Johtaja, kasvu ja uudistuminen

Pekka Koponen
Founder, CEO

Vuoden teknologiajohtaja -tunnustuspalkinto jaetaan jo kahdeksatta kertaa tunnustuksena teknologiajohtajalle, joka on työllään vaikuttanut yrityksensä teknologiakyvykkyyteen ja kasvumahdollisuuksiin, toimii inspiroivana johtajana sekä vaikuttaa aktiivisesti yhteiskunnallisissa verkostoissa. Palkinnon saajan valitsee Suomen teknologiavaikuttajista koostuva tuomaristo. Tuomariston puheenjohtajana toimii johtaja Laura Juvonen Teknologiateollisuus ry:stä. CTO-Forum on Suomen teknologiajohtajien yhteisö, joka kokoaa Suomen eri yritysten innovaatio- ja teknologiajohtajat verkostoitumaan, keskustelemaan ja jakamaan ideoita yli toimialarajojen. CTO-Forumin tavoitteena on kasvattaa yritysten ja teknologiajohtajien tekemän työn arvostusta ja tunnettuutta. CTO-Forumin järjestää ja tunnustuspalkinnon jakaa yhteistyössä Business Finland, Teknologiateollisuus ry ja Spinverse.




By News

Ecolab Inc., the global leader in water, hygiene and energy technologies and services has acquired a minority stake in Metgen OY. As part of the acquisition, Ecolab will be granted exclusive distribution rights globally for Metgen OY’s pulp and paper portfolio, as well as its wastewater enzyme portfolio. This business supplies differentiated custom blended enzymatic solutions to maximize biomass performance for various industries.

MetGen, headquartered in Kaarina, Finland, designs novel enzymatic solutions to improve energy efficiency and speed of processes in industries such as Pulp and Paper, Biofuels and Biochemicals.

“We are glad to welcome Ecolab as an investor in MetGen. Our business goals are fully aligned with Ecolab’s objective to support customers to achieve the best solutions in water technologies for the pulp and paper sector.  MetGen is excited to work together with the Ecolab team to accelerate market growth through the global introduction of innovative, sustainable enzymatic solutions in various business segments,” said Alex Michine, CEO of MetGen.

The investment provides Ecolab with access to innovative custom enzymes to help producers improve machine efficiency, water and energy savings, product quality and profitability. The terms of the transaction were not disclosed.

“We are excited to work with MetGen and implement their innovative products into our offerings to enhance Ecolab’s ability to provide value-added solutions for our customers in the Pulp and Paper Industry,” said Jerome Charton, senior vice president and general manager, Nalco Water global paper, Ecolab’s water management business.

For more information, please contact:

Alex Michine, CEO, MetGen Oy, +358 40 543 3740

skype: alexmichine

 About MetGen Oy

MetGen designs and markets novel enzymatic solutions for the most challenging of industrial conditions to address our customer’s specific challenges. MetGen’s enzymes – MetZyme® – are industrial, highly-active, natural catalysts that accelerate chemical reactions and company uses advances in genetic engineering and microbiology to adapt enzymes to harsh industrial conditions and to handle a variety of lignocellulosic substrates. MetGen aims to be a widely recognized supplier of industrial enzymes, significantly contributing to the economics and sustainability of process industries such as pulp & paper, biofuels and biochemicals. MetGen’s competitive advantage is in tailoring or adapting enzymes to meet customer’s specific needs.

About Ecolab

A trusted partner at more than one million customer locations, Ecolab (ECL) is the global leader in water, hygiene and energy technologies and services that protect people and vital resources. With 2016 sales of $13 billion and 48,000 associates, Ecolab delivers comprehensive solutions and on-site service to promote safe food, maintain clean environments, optimize water and energy use, and improve operational efficiencies for customers in the food, healthcare, energy, hospitality and industrial markets in more than 170 countries around the world. Follow us on Twitter @ecolab, Facebook at, LinkedIn at Ecolab or Instagram at Ecolab Inc.

Technology Academy Finland awards Finnish biotech company: Millennium Distinction Award goes to MetGen, producer of industrial enzymes

By News

Technology Academy Finland (TAF) has given the Millennium Distinction Award to MetGen Oy, a company specialising in directed evolution, also known as protein engineering.

TAF awards the Millennium Distinction Award on alternate years with the Millennium Technology Prize. The Distinction is awarded to a company or researcher operating in Finland whose work is connected with the research field of the preceding winner of the Millennium Technology Prize. The 2016 Millennium Technology Prize was awarded to Professor Frances Arnold from the United States for developing a new and efficient method for creating proteins in the laboratory. Engineered proteins can be used to replace expensive or fossil-fuel-based production in many areas of industry. 2017 Millennium Distinction Award recipient MetGen also employs the methods pioneered by Professor Arnold.

“The one-million-euro Millennium Technology Prize is an international award of recognition, whereas the Millennium Distinction Award is designed to reward and showcase cutting-edge commercial applications and research in the same field in Finland,” says Ari Ahonen, CEO of Technology Academy Finland. “With this year’s Millennium Distinction Award we support a Finnish enterprise that is fast gaining international recognition and also participates in several sustainable EU projects.”

MetGen provides cleantech solutions for industry

Founded in 2008 in Kaarina, Finland, MetGen Oy provides enzymes to the constantly growing biomass market. The mission of the cleantech company is to empower businesses in employing faster and more energy-efficient processes by providing them with enzymes, proteins that function as catalysts also in nature. The advantage of the genetically engineered enzymes developed by MetGen is that they can withstand challenging conditions in industrial production, such as extreme pH values and high temperatures.

MetGen develops new enzymes for three sectors of the industry: pulp and paper industry, biofuels, and industrial waste water processing. In pulp production, for instance, savings in energy, cost and time are significant when the chips can be partially broken down with enzymes prior to pulping. Enzymes can also be used to manufacture bioethanol fuel from pulp production waste.

MetGen has excelled in utilizing advanced methods of directed evolution and protein engineering for benefit of green chemistry by aiming to reduce pollutants and the use of non-renewables in various industries.

“The great challenge for the future is to utilise all fractions of the biomass feedstock to produce chemicals and materials,” says Alex Michine, CEO of MetGen. “We are planning to address the full value-chain in bioprocessing, targeting zero waste performance and lowering the carbon footprint.”

MetGen has previously won other awards, including the European John Sime Award for Most Innovative Technology of 2016. Moreover, in 2014 the Global Cleantech Cluster Association named MetGen one of the top 10 cleantech cluster companies in the world.

“It is an honour and a privilege to receive the Millennium Distinction Award. We see this award as a huge motivator to contribute even more to further growth of sustainable bioeconomy”, says CEO Alex Michine.

Technology Academy Finland TAF will present the Millennium Distinction Award in cooperation with the City of Turku, Turku Science Park, Turku University of Applied Sciences, University of Turku and Åbo Akademi on 2 November 2017 at 18.00 at Turku City Hall. Representatives of the media are welcome to attend.

The next Millennium Technology Prize will be awarded on 22 May 2018.


Technology Academy Finland (TAF)
Ari Ahonen, CEO,, tel. +358 40 061 8300
Media relations: Laura Manas, Communications Manager,, tel. +358 500 989 286


Christine Hagström-Näsi, Senior Advisor, Click Innovation Oy
Mart Saarma, Professor, University of Helsinki
Jukka Seppälä, Professor, Aalto University

Sweetwater Energy Announces Licensing Agreement for MetGen’s Groundbreaking Lignin Fractionation Technology

By News

Sweetwater Energy, Inc., a Rochester NY-based renewable bio-products producer, has finalized a licensing and joint technology development agreement with the Finnish company MetGen Oy. Cooperation will allow the development of a full range of high value lignin-based products including resins and adhesives, foams and composites and bio-based chemicals and polymers to meet the growing needs of a fast changing world.

MetGen is a pioneer in lignocellulosic industrial enzymes and renewable chemicals. The license is for MetGen’s LIGNOTM technology platform which facilitates the enzymatic break down of Sweetwater’s ultra-clean lignin into its fundamental component parts. Sweetwater and MetGen will carry out the commercialization of both technology platforms at Sweetwater’s commercial facility in Rochester NY and will roll the technology out to facilities world-wide.

“By introducing highly profitable products produced from Sweetwater’s Ultra-ligninTM, we are advancing the global bioeconomy by economically competing directly with products from the petrochemical industry.  MetGen’s LIGNOTM technology will allow us to create high quality, low cost products that unlock the true value of the lignin.  The increased revenues from our high value lignin will also allow us to price wood-based cellulosic sugars at well below corn sugar for the first time in history. Cellulosic sugars can be used as renewable non-food resources for biochemical and biofuel industries” said Arunas Chesonis, Sweetwater’s Chairman and CEO.

MetGen’s CEO Alex Michine said “Over the past years MetGen has accumulated extensive experience on applying enzymes in industrial biorefineries. In this work, we have recognized how important it is to match the proper technologies throughout the value-chain. This is why we are excited about the pairing of Sweetwater’s Sunburst technology with our LIGNOTM platform.  Every processing step and every fraction of the raw material counts when creating renewable –and affordable – chemicals and materials out of lignocellulosic biomass.”

For more information, please contact:

Alex Michine, CEO, MetGen Oy
skype: alexmichine

About MetGen Oy

MetGen designs and markets novel enzymatic solutions for the most challenging of industrial conditions to address our customer’s specific challenges. MetGen was founded in 2008 and is based in Kaarina, Finland. MetGen’s enzymes – MetZyme® – are industrial, highly-active, natural catalysts that accelerate chemical reactions and company uses advances in genetic engineering and microbiology to adapt enzymes to harsh industrial conditions and to handle a variety of lignocellulosic substrates. MetGen aims to be a widely recognized supplier of industrial enzymes, significantly contributing to the economics and sustainability of process industries such as pulp & paper, biofuels and biochemicals. MetGen’s competitive advantage is in tailoring or adapting enzymes to meet customer’s specific needs.

About Sweetwater Energy Ltd.

Sweetwater Energy is a Rochester, NY-based company that has developed a unique and patented technology for producing low-cost sugars and clean lignin fiber from multiple non-food plant materials to help meet the modern world’s increasing demand for biochemicals, bioplastics and biofuels. Begun in 2009 in the Rochester Institute of Technology incubator, the company now has a comprehensive intellectual property portfolio of issued and pending patents around the modular approach to produce sugars and clean lignin that are both less expensive and substantially more favorable for the environment than competing products available today from petroleum and food crops.

The LIGNOTM field of application has been expanded to a wider pH range, with alkaliphilic enzymes that can effectively function at a pH up to 11.  This means that they function at a pH where lignin is fully soluble, with an added benefit of outstanding thermo-tolerance.  These advances allow the rapid production of smaller, more active and uniform aromatics. This fractionation of lignin suddenly enables drop-in solutions in coatings, plasticizers, polyurethanes, binders and fuels that have yet to be fully realized with existing crude lignin.